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[ Fonte: rna-star  ]

Pacote: rna-star (2.7.10b+dfsg-2 e outros)

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ultrafast universal RNA-seq aligner

Spliced Transcripts Alignment to a Reference (STAR) software based on a previously undescribed RNA-seq alignment algorithm that uses sequential maximum mappable seed search in uncompressed suffix arrays followed by seed clustering and stitching procedure. STAR outperforms other aligners by a factor of >50 in mapping speed, aligning to the human genome 550 million 2 × 76 bp paired-end reads per hour on a modest 12-core server, while at the same time improving alignment sensitivity and precision. In addition to unbiased de novo detection of canonical junctions, STAR can discover non-canonical splices and chimeric (fusion) transcripts, and is also capable of mapping full-length RNA sequences. Using Roche 454 sequencing of reverse transcription polymerase chain reaction amplicons, the authors experimentally validated 1960 novel intergenic splice junctions with an 80-90% success rate, corroborating the high precision of the STAR mapping strategy.

Etiquetas: Biologia: Ácidos nucleicos, Campo: Biologia, field::biology:bioinformatics, implemented-in::c++, Função: Programa, Propósito: use::analysing, works-with::biological-sequence

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Download de rna-star

Baixe para todas as arquiteturas disponíveis
Arquitetura Versão Tamanho do pacote Tamanho instalado Arquivos
amd64 2.7.10b+dfsg-2+b2 3,366.2 kB21,813.0 kB [lista de arquivos]
arm64 2.7.10b+dfsg-2+b2 687.6 kB2,567.0 kB [lista de arquivos]
mips64el 2.7.10b+dfsg-2+b2 671.8 kB3,133.0 kB [lista de arquivos]
ppc64el 2.7.10b+dfsg-2+b2 748.8 kB3,079.0 kB [lista de arquivos]