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[ Zdroj: bio-eagle  ]

Balík: bio-eagle (2.4.1-3 a iné)

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Haplotype phasing within a genotyped cohort or using a phased reference panel

Eagle estimates haplotype phase either within a genotyped cohort or using a phased reference panel. The basic idea of the Eagle1 algorithm is to harness identity-by-descent among distant relatives—which is pervasive at very large sample sizes but rare among smaller numbers of samples—to rapidly call phase using a fast scoring approach. In contrast, the Eagle2 algorithm analyzes a full probabilistic model similar to the diploid Li-Stephens model used by previous HMM-based methods.

Please note: The executable was renamed to bio-eagle because of a name clash. Please read more about this in /usr/share/doc/bio-eagle/README.Debian.

Značky: Pole: Biológia, Bioinformatika, Implementované v: implemented-in::c++, interface::commandline, Role: Program, Purpose: Analyzovanie

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i386 2.4.1-3+b1 244.9 kB674.0 kB [zoznam súborov]