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[ Source: libtfbs-perl  ]

Пакунок: libtfbs-perl (0.7.1+ds-4 and others)

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scanning DNA sequence with a position weight matrix

The TFBS perl modules comprise a set of routines to interact with the Transfac and Jaspar databases that describe a special family of proteins, the transcription factors. These bind to genomic DNA to initiate (or prevent) the readout of a gene. Once multiple binding sites are known for a transcription factor, these are gathered in a single file and are aligned in order to find position-specific characteristica that might be used to predict such binding events in novel DNA sequences.

If you use TFBS in your work, please cite "Lenhard B., Wasserman W.W. (2002) TFBS: Computational framework for transcription factor binding site analysis. Bioinformatics 18:1135-1136".

Note: the TFBS perl module is no longer under active development. All the functionality can be found in the TFBSTools Bioconductor package; users are highly encouraged to switch. <http://bioconductor.org/packages/TFBSTools/>

Tags: Software Development: Perl Development, Бібліотеки, Field: field::biology, field::biology:bioinformatics, Implemented in: C, implemented-in::perl, interface::commandline, Role: Development Library, Program

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