Balík: gemma (0.98.4+dfsg-4)

[ Zdroj: gemma  ]

Genome-wide Efficient Mixed Model Association

GEMMA is the software implementing the Genome-wide Efficient Mixed Model Association algorithm for a standard linear mixed model and some of its close relatives for genome-wide association studies (GWAS):

 * It fits a univariate linear mixed model (LMM) for marker association
   tests with a single phenotype to account for population stratification
   and sample structure, and for estimating the proportion of variance in
   phenotypes explained (PVE) by typed genotypes (i.e. "chip heritability").
 * It fits a multivariate linear mixed model (mvLMM) for testing marker
   associations with multiple phenotypes simultaneously while controlling
   for population stratification, and for estimating genetic correlations
   among complex phenotypes.
 * It fits a Bayesian sparse linear mixed model (BSLMM) using Markov
   chain Monte Carlo (MCMC) for estimating PVE by typed genotypes,
   predicting phenotypes, and identifying associated markers by jointly
   modeling all markers while controlling for population structure.
 * It estimates variance component/chip heritability, and partitions
   it by different SNP functional categories. In particular, it uses HE
   regression or REML AI algorithm to estimate variance components when
   individual-level data are available. It uses MQS to estimate variance
   components when only summary statisics are available.

GEMMA is computationally efficient for large scale GWAS and uses freely available open-source numerical libraries.

Ostatné balíky súvisiace s balíkom gemma

• dep: libc6 (>= 2.29)

  knižnica GNU C - zdieľané knižnice
  tiež virtuálny balík poskytovaný balíkom libc6-udeb

• dep: libgcc-s1 (>= 3.0) [nie armhf]

  podporná knižnica GCC

  dep: libgcc-s1 (>= 3.5) [armhf]

• dep: libgsl25 (>= 2.6)

  GNU Scientific Library (GSL) - balík knižnice

• dep: libopenblas0

  Optimized BLAS (linear algebra) library (meta)

• dep: libstdc++6 (>= 5.2) [armhf]

  štandardná knižnica C++ GNU v3

  dep: libstdc++6 (>= 9) [nie armhf]

• dep: zlib1g (>= 1:1.1.4)

  komprimačná knižnica - dynamická verzia

Stiahnuť gemma

Stiahnuť pre všetky dostupné architektúry

Architektúra	Veľkosť balíka	Nainštalovaná veľkosť	Súbory
amd64	396.5 kB	1,184.0 kB	[zoznam súborov]
arm64	332.2 kB	1,008.0 kB	[zoznam súborov]
armhf	341.7 kB	742.0 kB	[zoznam súborov]
i386	414.0 kB	1,289.0 kB	[zoznam súborov]
mips64el	337.3 kB	1,354.0 kB	[zoznam súborov]
ppc64el	385.8 kB	1,372.0 kB	[zoznam súborov]
s390x	337.0 kB	1,167.0 kB	[zoznam súborov]