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套件:ngmlr(0.2.7+git20210816.a2a31fb+dfsg-4~0exp0simde) [debports]

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警告:這個套件來自於 experimental 發行版。這表示它很有可能表現出不穩定或者出現 bug ,甚至是導致資料損失。請務必在使用之前查閱 changelog 以及其他潛在的文件。

CoNvex Gap-cost alignMents for Long Reads

Ngmlr is a long-read mapper designed to sensitively align PacBilo or Oxford Nanopore to (large) reference genomes. It was designed to quickly and correctly align the reads, including those spanning (complex) structural variations. Ngmlr uses an SV aware k-mer search to find approximate mapping locations for a read and then a banded Smith- Waterman alignment algorithm to compute the final alignment. Ngmlr uses a convex gap cost model that penalizes gap extensions for longer gaps less than for shorter ones to compute precise alignments.

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