[ 源代码: vcfanno ]
软件包:vcfanno(0.3.2+ds-2 以及其他的)
annotate a VCF with other VCFs/BEDs/tabixed files
Vcfanno allows you to quickly annotate your VCF with any number of INFO fields from any number of VCFs or BED files. It uses a simple conf file to allow the user to specify the source annotation files and fields and how they will be added to the info of the query VCF.
* For VCF, values are pulled by name from the INFO field with special cases of ID and FILTER to pull from those VCF columns. * For BED, values are pulled from (1-based) column number. * For BAM, depth (count), "mapq" and "seq" are currently supported.
Vcfanno is written in go and it supports custom user-scripts written in Lua. It can annotate more than 8000 variants per second with 34 annotations from 9 files on a modest laptop and over 30K variants per second using 12 processes on a server.