软件包：hisat2（2.2.1-4 以及其他的）
graph-based alignment of short nucleotide reads to many genomes
HISAT2 is a fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as against a single reference genome). Based on an extension of BWT for graphs a graph FM index (GFM) was designed and implementd. In addition to using one global GFM index that represents a population of human genomes, HISAT2 uses a large set of small GFM indexes that collectively cover the whole genome (each index representing a genomic region of 56 Kbp, with 55,000 indexes needed to cover the human population). These small indexes (called local indexes), combined with several alignment strategies, enable rapid and accurate alignment of sequencing reads. This new indexing scheme is called a Hierarchical Graph FM index (HGFM).
其他与 hisat2 有关的软件包
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- dep: libc6 (>= 2.34)
- GNU C 语言运行库：共享库
同时作为一个虚包由这些包填实： libc6-udeb
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- dep: libgcc-s1 (>= 3.0)
- GCC 支持库
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- dep: libstdc++6 (>= 11)
- GNU 标准 C++ 库，第3版
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- dep: perl
- 拉里 沃尔的实用报表提取语言(Perl)
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- dep: python3
- interactive high-level object-oriented language (default python3 version)
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- rec: bcftools
- genomic variant calling and manipulation of VCF/BCF files
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- rec: python3-hisat2
- Python scripts accompanying hisat2
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- rec: samtools
- processing sequence alignments in SAM, BAM and CRAM formats