Package: melting (5.2.0-2)

[ Source: melting  ]

compute the melting temperature of nucleic acid duplex

This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough.

Tags: Field: Biology, Bioinformatics, field::biology:molecular, implemented-in::c, User Interface: Command Line, Role: role::program, scope::utility, Application Suite: GNU, Purpose: use::analysing, works-with-format::plaintext, Works with: Need an extra tag

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