Genome-Wide Association Meta Analysis
GWAMA (Genome-Wide Association Meta Analysis) software performs
meta-analysis of the results of GWA studies of binary or
quantitative phenotypes. Fixed- and random-effect meta-analyses are
performed for both directly genotyped and imputed SNPs using
estimates of the allelic odds ratio and 95% confidence interval for
binary traits, and estimates of the allelic effect size and standard
error for quantitative phenotypes. GWAMA can be used for analysing
the results of all different genetic models (multiplicative,
additive, dominant, recessive). The software incorporates error
trapping facilities to identify strand alignment errors and allele
flipping, and performs tests of heterogeneity of effects between studies.
