Pakiet: r-bioc-pfamanalyzer (1.4.0+dfsg-1)

[ Pakiet źródłowy: r-bioc-pfamanalyzer  ]

GNU R identification of domain isotypes in pfam data

Protein domains is one of the most import annoation of proteins that are with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. It was recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease- specific manner. Accordingly, it was found that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data.

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