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[ Quellcode: r-cran-alakazam  ]

Paket: r-cran-alakazam (1.3.0-2~0exp0)

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Warnung: Dieses Paket stammt aus der Experimental-Distribution. Dies bedeutet, dass es höchstwahrscheinlich instabil oder fehlerhaft ist und sogar Datenverlust verursachen kann. Bitte lesen Sie den Changelog und andere möglicherweise verfügbare Dokumentation, bevor Sie es benutzen.

Immunoglobulin Clonal Lineage and Diversity Analysis

Alakazam is part of the Immcantation analysis framework for Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) and provides a set of tools to investigate lymphocyte receptor clonal lineages, diversity, gene usage, and other repertoire level properties, with a focus on high-throughput immunoglobulin (Ig) sequencing.

Alakazam serves five main purposes:

 * Providing core functionality for other R packages in the Immcantation
   framework. This includes common tasks such as file I/O, basic DNA
   sequence manipulation, and interacting with V(D)J segment and gene
   annotations.
 * Providing an R interface for interacting with the output of the
   pRESTO and Change-O tool suites.
 * Performing lineage reconstruction on clonal populations of Ig
   sequences and analyzing the topology of the resultant lineage trees.
 * Performing clonal abundance and diversity analysis on lymphocyte
   repertoires.
 * Performing physicochemical property analyses of lymphocyte receptor
   sequences.

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